Weight Loss
Providing Medically Supervised Weight loss
According to the CDC in 2016, more than one-third of Americans are obese.
Obesity-related conditions include heart disease, stroke, type 2 diabetes and certain types of cancer, some of the leading causes of preventable death.
The most common causes of obesity:
- Excessive carbohydrate intake
- Hormone imbalance
- Food allergies
- Side effects from medications
- Eating out of stress or depression
- Lack of exercise
- Insulin Resistance
What is Insulin Resistance?
- Insulin signals muscle, fat and liver to uptake glucose into the cell. Also signals liver to stop making glucose.
- Insulin resistance is the impaired ability to do any of this in the presence of insulin.
- Insulin resistance is a continuum. Hyperinsulinemia→impaired glucose disposal→Nonalcoholic fatty liver disease (NAFLD)→Nonalcoholic Steatohepatitis (NASH)→Type 2 Diabete Melitis (T2DM).
- Progression goes from insulin resistance in the muscle to insulin resistance in the liver and then type 2 diabetes.
- Insulin resistant participants were able to store far less muscle glycogen meaning difficulty building or maintaining muscle.
Criteria for Metabolic syndrome (IR)
- Waist circumference more than 40 inches in men and 35 inches in women
- Elevated triglycerides 150 milligrams per deciliter of blood (mg/dL) or greater
- Reduced high-density lipoprotein cholesterol (HDL) less than 40 mg/dL in men or less than 50 mg/dL in women
- Elevated fasting glucose of l00 mg/dL or greater
- Blood pressure values of systolic 130 mmHg or higher and/or diastolic 85 mmHg or higher
We are in the midst of a serious obesity epidemic. At The Wellness Firm, PLLC we are trained in not just in weight loss but also in hormone balance, gut restoration, and sleep management. All things that factor into causes of weight gain or inability to lose the weight. We are dedicated to helping the community lose weight through diet, exercise, correcting underlying medical conditions, and the use of medications to help with hunger and behaviour modification. A healthy weight loss of 1-2 pounds a week has been shown to be the most effective. Losing weight is not easy. But even a modest 5-10% decrease in weight reduction is likely to produce significant health benefits according to the CDC. If you are serious about losing weight, call for your appointment today.
Take that first step by calling us at (409) 730-7005.

What Is the Best GLP-1 for Weight Loss?
There isn’t a one-size-fits-all “best” GLP-1 receptor agonist for weight loss, as the optimal choice depends on individual factors like your medical history, tolerance to side effects, cost, insurance coverage, and specific health goals (e.g., diabetes management alongside weight loss). However, based on the latest clinical trials and real-world data as of July 2025, tirzepatide consistently outperforms other GLP-1 medications in terms of average weight loss achieved. It’s a dual agonist targeting both GLP-1 and GIP (glucose-dependent insulinotropic polypeptide) receptors, which enhances its effects on appetite suppression, satiety, and metabolism compared to single GLP-1 agonists like semaglutide or liraglutide.
Tirzepatide is more effective than Semaglutide for treatment of obesity mainly because the former combines both GLP-1 and GIP. The physiology of #GIP is described here… Oxford Academic https://t.co/am9ixC1I5B
— Neil Floch MD (@NeilFlochMD) February 15, 2025
Battle of the weight loss giants . . . and other research https://t.co/M0y89QiqDF
— Truthoverdishonesty (@Nigelj08223326) July 24, 2025
Average weight loss with semaglutide after 72 weeks was 13.7% versus 20.2% with tirzepatide@reesprescribe @DrIanWeissman @ParagSinghal09
🏆 Tirzepatide vs. Semaglutide
— Michael Albert, MD (@MichaelAlbertMD) May 13, 2025
The heavyweight bout we’ve all been waiting for—and it’s a TKO.
- - -
A new NEJM study just dropped the first head-to-head trial in people with obesity (no diabetes).
Here’s how it played out over 72 weeks:
🥇 Tirzepatide (Zepbound) vs 🥈… pic.twitter.com/qihQkv82to
Read more from the Pharmacy Times Clinical Forum using the link below.
— Pharmacy Times (@Pharmacy_Times) July 24, 2025
Semaglutide & tirzepatide are transforming diabetes & obesity management. These GLP-1 receptor agonists offer benefits from glycemic control to weight loss and cardiovascular risk reduction, emphasizing their… pic.twitter.com/gGsrv2LjEW
New study result 🚨
— Michael Weintraub, MD (@MWeintraubMD) May 12, 2025
Tirzepatide vs semaglutide SURMOUNT 5 RCT
📉Total body weight loss:
−20.2% with tirzepatide
−13.7% with semaglutide
🤢Discontinuations due to gastrointestinal events: tirzepatide 2.7%, semaglutide 5.6%
🤮vomiting tirzepatide 15.0% vs semaglutide 21.3%… pic.twitter.com/ydJdklmFv7
Tirzepatide is just such an amazing drug!
— Conrad Fischer (@SeeFisch) March 25, 2023
*First ever COMBINE GLP and GIP drug
*2-2.5% decrease in HgA1c
*15-20% weight loss!!!!!!!!!!!!!!!!!!!!!!!!!!!!
🦉 Tirzepatide activates both GIP and GLP-1 receptors. Early data shows superior glucose and weight loss outcomes vs. semaglutide. Triple agonists targeting GLP-1/GIP/glucagon are under development.
— aponia_analytics (@AponiaAnalytics) July 20, 2025
https://t.co/9TOGfOnYyw#Tirzepatide #obesity $NVO $LLY $AZN $SNY $GSK $PFE…
GLP-1 medications work by mimicking the glucagon-like peptide-1 hormone, which regulates appetite, slows gastric emptying, and improves insulin sensitivity. They’re FDA-approved for chronic weight management in adults with obesity (BMI ≥30) or overweight (BMI ≥27) with weight-related conditions. All require lifestyle changes (diet, exercise) for best results, and weight regain often occurs upon discontinuation.
Below, I’ll compare the top GLP-1 options for weight loss based on 2025 data, focusing on effectiveness, side effects, dosing, and other considerations. Data comes from head-to-head trials like SURMOUNT-5 (tirzepatide vs. semaglutide) and meta-analyses.
Key Comparison of GLP-1 Medications for Weight Loss
| Medication | Brand Name (for Weight Loss) | Mechanism | Average Weight Loss (in Trials) | Dosing | Common Side Effects | Cost & Availability (2025) | Best For |
|---|---|---|---|---|---|---|---|
| Tirzepatide | Zepbound | Dual GLP-1/GIP agonist | 20-25% body weight loss over 72 weeks (e.g., 20.2% in SURMOUNT-5; up to 22.5% in SURMOUNT-1) | Weekly injection (5-15 mg) | Nausea, diarrhea, vomiting (15-20% rate, often mild); lower discontinuation vs. semaglutide | $1,000-1,300/month (20% less than semaglutide); shortages easing but high demand | Those seeking maximum weight loss; superior for obesity without diabetes; better waist reduction (-18.4 cm) |
| Semaglutide | Wegovy | GLP-1 agonist | 13-20% body weight loss over 68-72 weeks (e.g., 13.7% in SURMOUNT-5; 14.9% in STEP-1) | Weekly injection (0.25-2.4 mg) | Similar GI issues (nausea 20-25%, vomiting 21%); higher discontinuation in some trials | $1,300-1,500/month; widely available, including oral form (Rybelsus) | Proven long-term data; good for diabetes + weight loss; cardiovascular benefits |
| Liraglutide | Saxenda | GLP-1 agonist | 5-10% body weight loss over 56 weeks (e.g., 8% in SCALE trial) | Daily injection (up to 3 mg) | GI side effects (similar but daily dosing may increase nausea); higher dropout rates | $1,000-1,400/month; generic options emerging | Entry-level option; less effective but suitable for milder cases or needle-phobic patients (daily vs. weekly) |
- Why Tirzepatide Is Often Considered the Best: In direct comparisons, tirzepatide leads to 47% greater relative weight reduction than semaglutide, with more patients achieving ≥20% loss (48% vs. 27%). It’s particularly effective for non-diabetic obesity, reducing waist circumference more and improving metabolic markers like blood sugar. Real-world X discussions from doctors echo this, noting its dual mechanism makes it “transformational” and “superior.”
- Other Considerations:
- Side Effects: All GLP-1s cause gastrointestinal issues (nausea, vomiting, diarrhea), but tirzepatide may have slightly lower rates in some trials (e.g., 2.7% discontinuation vs. 5.6% for semaglutide). Rare risks include pancreatitis or thyroid tumors—discuss with a doctor.
- Muscle Loss: Up to 25-40% of weight loss can be lean mass; pair with resistance training to preserve muscle.
- Cost and Access: High prices limit access; tirzepatide is cheaper but faces shortages. Compounded versions exist but carry risks.
- Alternatives: Newer options like retatrutide (triple agonist) are in trials but not yet approved. Bariatric surgery may outperform GLP-1s long-term (e.g., 5x more weight loss).
Always consult a healthcare provider before starting any GLP-1 medication, as they can cause serious side effects and aren’t suitable for everyone (e.g., history of medullary thyroid cancer). If you’re considering options, a specialist can help determine the best fit based on your profile.
Most Commonly Asked Weight Loss Questions
Weight loss is a topic that generates countless weight loss questions, as people seek effective, sustainable strategies amid a sea of myths and conflicting advice. Based on insights from health experts, online forums, and social media discussions, here are the top 10 most frequently asked weight loss questions about weight loss. I’ve drawn from reliable sources like medical websites, Reddit communities, and real-time social media trends to compile this list. At The Wellness Firm in Lumberton, TX, led by Mary Ann Butler, APRN, we address these concerns through personalized programs, including GLP-1 medications (e.g., semaglutide, tirzepatide), hormone optimization, and peptide therapy. Our holistic approach combines science-backed treatments with nutrition coaching to help you achieve lasting results.
1. How Do I Start Losing Weight?
This is often the first hurdle for beginners. The key is creating a calorie deficit—consuming fewer calories than you burn—while focusing on whole foods, portion control, and gradual changes. Start by tracking your intake with apps like MyFitnessPal and aiming for 1-2 pounds of loss per week. At The Wellness Firm, we begin with a comprehensive assessment, including metabolic testing, to set realistic goals tailored to your needs.
2. How Many Calories Should I Eat Per Day to Lose Weight?
Calorie needs vary by age, gender, height, weight, and activity level. A general rule: Women should aim for at least 1,200 calories daily, and men 1,500, to avoid nutrient deficiencies. Use online calculators to estimate your Total Daily Energy Expenditure (TDEE) and subtract 500 calories for safe loss. Mary Ann Butler, APRN, customizes calorie plans based on your hormone levels and metabolism, often integrating GLP-1 therapy to naturally reduce appetite and support a deficit.
3. Does Exercise Alone Lead to Weight Loss, or Is Diet More Important?
Diet is typically 80% of the equation, as it’s easier to cut calories than burn them through exercise. However, combining both is ideal—exercise like strength training preserves muscle and boosts metabolism. On social media, users emphasize that “exercise doesn’t cause weight loss but is great for health.” Our programs at The Wellness Firm include resistance training recommendations to complement GLP-1 treatments, ensuring fat loss over muscle loss.
4. What If I Hit a Weight Loss Plateau?
Plateaus occur when your body adapts to a deficit, often due to metabolic slowdown, water retention, or inaccurate tracking. Reassess your calories, measure portions with a food scale, and incorporate strength training. Short-term stalls (e.g., from exercise-induced inflammation) are normal—track trends over weeks. X users note that “metabolic adaptation” (not “starvation mode”) is the real issue, with solutions like refeeds or thyroid checks. We monitor progress at The Wellness Firm and adjust GLP-1 dosing or add peptide therapy to break through plateaus.
5. Is “Starvation Mode” Real, and Is It Safe to Eat Very Few Calories?
“Starvation mode” is a myth—your body doesn’t stop burning fat from low calories alone, but extreme restriction (<1,000 calories) can lead to nutrient deficiencies, muscle loss, and health risks like hair loss or anemia. Stick to minimums of 1,200 for women and 1,500 for men without medical supervision. Social discussions confirm it’s “metabolic adaptation,” not a shutdown, and advise precise tracking. Our supervised GLP-1 programs ensure safe deficits without risking malnutrition.
6. How Can I Stay Motivated During Weight Loss?
Motivation wanes, so rely on discipline: Set small goals, track non-scale victories (e.g., energy levels), and build habits like meal prepping. List pros/cons of change and address emotional eating. X tips include mindset shifts and avoiding fad diets. At The Wellness Firm, we provide behavioral coaching and telehealth support to keep you accountable.
7. Do Weight Loss Medications Like GLP-1s Work, and How Long Do I Need Them?
GLP-1 medications (e.g., semaglutide) reduce appetite and support 15-25% weight loss by mimicking hormones that regulate hunger and metabolism. They’re often long-term for chronic obesity, but results vary—combine with lifestyle changes to avoid regain upon stopping. Questions about side effects (e.g., nausea) and duration are common. Mary Ann Butler, APRN, specializes in these at The Wellness Firm, with expert monitoring for safety.
8. Can I Lose Weight Without Giving Up Certain Foods or Eating at Night?
Yes—focus on moderation and overall calories, not strict bans. Myths like “no eating after 8 PM” or “must go low-carb” aren’t necessary for everyone. Include favorites in portions that fit your deficit. Our nutritionists help craft flexible plans.
9. Why Am I Gaining Weight When I Start Exercising?
Initial gains are often water retention from muscle repair or inflammation, not fat. It subsides after 4-6 weeks—focus on measurements, not the scale. X users advise patience and tracking trends.
10. How Can I Stop Binge Eating or Emotional Eating?
Binges stem from restriction, stress, or habits—ensure adequate calories, prioritize protein for satiety, and address triggers with mindfulness or therapy. GLP-1s at The Wellness Firm reduce cravings, aiding control.
For personalized answers, schedule a free consultation at The Wellness Firm in Lumberton, TX. Contact us at 100 Canyon Lake Cir or via telehealth—Mary Ann Butler, APRN, can guide your journey with GLP-1, hormone, and peptide expertise.
Disclaimer: This is educational; consult a provider for tailored advice.
Determining a healthy weight depends on several individual factors, including your height, age, gender, body composition (muscle mass vs. fat), and overall health status. Since you haven’t provided specific personal details (e.g., height, age, or gender), I’ll offer a comprehensive guide to help you understand what constitutes a healthy weight and how The Wellness Firm in Lumberton, TX, led by Mary Ann Butler, APRN, can assist you in achieving it through personalized GLP-1 weight loss programs and holistic care, including advice on what is a healthy weight for me. If you provide more details (e.g., height, age, or health goals), I can tailor this further. Understanding what is a healthy weight for me is essential for effective health management.
Understanding what is a healthy weight for me is crucial for setting realistic health goals and ensuring optimal health outcomes.
Understanding Healthy Weight
What is a Healthy Weight for Me?
A “healthy weight” is typically defined as a weight range that reduces the risk of chronic diseases (e.g., diabetes, heart disease) and supports overall well-being. It’s not a one-size-fits-all number, as it varies based on individual factors. Common methods to assess healthy weight include:
When considering what is a healthy weight for me, it’s important to remember that individual variations play a significant role.
- Body Mass Index (BMI):
- What it is: BMI is a widely used tool that calculates weight in relation to height. It’s expressed as weight in kilograms divided by height in meters squared (kg/m²).
- Healthy Range: A BMI of 18.5–24.9 is considered healthy for most adults. Below 18.5 is underweight, 25–29.9 is overweight, and 30 or higher is obese.
- Limitations: BMI doesn’t account for muscle mass, bone density, or fat distribution. For example, athletes with high muscle mass may have a higher BMI but be healthy.
- Example: For a person who is 5’6” (1.68 meters) tall:
- Healthy weight range: Approximately 115–154 pounds (52–70 kg) for a BMI of 18.5–24.9.
- Formula: Weight (kg) ÷ [Height (m)]². To calculate for yourself, use an online BMI calculator or provide your height for a specific range.
- Body Fat Percentage:
- What it is: This measures the proportion of fat versus lean mass (muscle, bones, organs). It’s more accurate than BMI for assessing health, as it reflects body composition.
- Healthy Ranges:
- Women: 21–33% (ages 20–39), 23–35% (ages 40–59).
- Men: 8–20% (ages 20–39), 11–23% (ages 40–59).
- Assessment: At The Wellness Firm, we use advanced diagnostic tools (e.g., body composition analysis) to measure body fat and tailor weight loss plans.
- Waist-to-Height Ratio:
- What it is: This measures waist circumference relative to height, indicating visceral fat (fat around organs), which is linked to health risks.
- Healthy Range: A waist circumference less than half your height is ideal (e.g., a 5’6” person should have a waist under 33 inches).
- Why it matters: Excess visceral fat increases risks for diabetes and heart disease, which GLP-1 medications can help address.
- Individual Health Factors:
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- Medical Conditions: Conditions like type 2 diabetes, insulin resistance, or hormonal imbalances (e.g., PCOS, thyroid issues) can influence your ideal weight. Mary Ann Butler, APRN, specializes in hormone optimization and peptide therapy, addressing these factors to support healthy weight goals.
At The Wellness Firm, we help you explore what is a healthy weight for me by considering various health metrics.
- Lifestyle and Goals: Your activity level, muscle mass, and personal goals (e.g., aesthetics vs. health) impact what’s “healthy” for you.
- Age and Gender: Metabolism slows with age, and women typically have higher body fat percentages than men, affecting weight targets.
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How GLP-1 Medications Support a Healthy Weight at The Wellness Firm
At The Wellness Firm in Lumberton, TX, we recognize that achieving a healthy weight is about more than just a number on the scale. Our GLP-1 weight loss programs, led by Mary Ann Butler, APRN, a certified expert in hormone optimization and peptide therapy, are designed to help you reach and maintain a healthy weight through personalized, science-backed solutions. Here’s how GLP-1 medications (e.g., semaglutide, tirzepatide) contribute:
- Targeting a Healthy Weight:
- Appetite Regulation: GLP-1 medications reduce hunger and cravings by acting on the brain’s hypothalamus, helping you consume fewer calories without feeling deprived. This supports gradual weight loss toward a healthy BMI or body fat percentage.
- Enhanced Satiety: By slowing gastric emptying, GLP-1s make you feel full longer, reducing snacking and supporting a calorie deficit. For example, patients may lose 10–20% of body weight with semaglutide or up to 25% with tirzepatide over 6–12 months.
- Metabolic Health: GLP-1s improve insulin sensitivity and blood sugar control, which can reduce fat storage and help you achieve a weight that lowers chronic disease risks.
- Personalized Assessment:
- During your consultation at The Wellness Firm, Mary Ann Butler, APRN, conducts a comprehensive evaluation, including:
- BMI and Body Composition: To determine your current weight status and set realistic goals.
- Hormonal and Metabolic Testing: To identify imbalances (e.g., insulin resistance, thyroid dysfunction) that affect weight.
- Health History Review: To account for conditions like diabetes or PCOS, ensuring your target weight aligns with overall health.
- Based on this, we calculate a personalized healthy weight range, considering BMI, body fat percentage, and waist-to-height ratio.
- During your consultation at The Wellness Firm, Mary Ann Butler, APRN, conducts a comprehensive evaluation, including:
- Holistic Support for Sustainable Results:
- Hormone Optimization: As a BioTE-certified provider, Butler addresses hormonal imbalances that hinder weight loss, such as low testosterone or estrogen imbalances, which can affect body composition.
- Peptide Therapy: Our A4M-certified peptide treatments enhance fat loss, muscle retention, and metabolism, complementing GLP-1 therapy.
- Nutrition and Lifestyle Coaching: Our certified nutritionists create tailored meal plans, and we provide exercise and behavioral coaching to ensure you maintain a healthy weight long-term.
- Local and Telehealth Care: Serving Lumberton and Beaumont, TX, we offer in-person and telehealth consultations, making it easy to stay on track.
Factors That Influence Your Healthy Weight
Each person’s journey to discover what is a healthy weight for me is unique and shaped by personal experiences.
Since I don’t have your specific details, here are key factors we consider at The Wellness Firm to determine a healthy weight:
- Height: Taller individuals have a higher healthy weight range. For example, a 5’2” woman has a healthy weight of 104–136 pounds (BMI 18.5–24.9), while a 6’0” man’s range is 136–184 pounds.
- Age: Metabolism slows with age, so older adults may aim for the higher end of the BMI range to maintain muscle mass and bone health.
- Gender: Women typically have higher body fat percentages (21–33% healthy range) than men (8–20%), affecting ideal weight.
- Activity Level: Active individuals with more muscle mass may weigh more but still be healthy due to lower body fat.
- Health Conditions: Conditions like insulin resistance or hypothyroidism, common in Lumberton patients, may require a lower weight to reduce health risks.
- Genetics and Body Type: Genetic factors, such as those affecting metabolism or fat distribution, influence your ideal weight. (From prior conversations, you mentioned blood type O Positive and BCMO1/FUT2 mutations, suggesting a diet rich in animal-based proteins and Vitamin A/B12 may support your weight goals, which we can incorporate into your plan.)
Typical Healthy Weight Ranges
To provide a general idea, here are healthy weight ranges based on BMI for common heights (assuming an adult):
- 5’0” (152 cm): 95–128 pounds (43–58 kg)
- 5’4” (163 cm): 108–145 pounds (49–66 kg)
- 5’8” (173 cm): 122–164 pounds (55–74 kg)
- 6’0” (183 cm): 136–184 pounds (62–83 kg)
These ranges are based on a BMI of 18.5–24.9. To get a precise range, please share your height, age, and gender, or schedule a consultation with The Wellness Firm for a personalized assessment.
Risks of Being Outside a Healthy Weight
- Underweight (BMI <18.5): May lead to nutrient deficiencies, weakened immunity, or fertility issues. Our team can help you gain weight healthily if needed.
- Overweight/Obese (BMI ≥25): Increases risks for diabetes, heart disease, and joint issues. GLP-1 medications at The Wellness Firm are particularly effective for patients with a BMI of 30 or higher (or 27+ with conditions like diabetes), helping reduce these risks.
- Visceral Fat: Even within a “normal” BMI, excess waist circumference (e.g., >35 inches for women, >40 inches for men) indicates health risks, which our GLP-1 and hormone therapies address.
How The Wellness Firm Helps You Achieve a Healthy Weight
At The Wellness Firm, we go beyond generic weight loss solutions. Here’s how we support you:
- Personalized GLP-1 Therapy: Mary Ann Butler, APRN, prescribes and monitors semaglutide or tirzepatide, starting with a low dose to minimize side effects (e.g., nausea) and titrating to an effective dose (e.g., 2.4 mg weekly for semaglutide). Patients typically see 10–25% weight loss over 6–12 months.
- Hormone and Peptide Integration: We address hormonal imbalances and use peptide therapies to enhance fat loss and metabolism, setting us apart from competitors like Genesis Lifestyle Medicine.
- Comprehensive Assessments: We use body composition analysis, blood work, and waist-to-height measurements to set a healthy weight goal tailored to you.
- Ongoing Support: Our telehealth services and home medication delivery make it easy for Lumberton and Beaumont patients to stay on track.
- Sustainability: Our nutrition and lifestyle coaching, combined with GLP-1 therapy, helps you maintain a healthy weight long-term, addressing the weight regain risk noted in STEP trials.
Next Steps
Ready to find out what is a healthy weight for me? Let’s start your journey together.
To determine your healthy weight and start your journey, contact The Wellness Firm at 100 Canyon Lake Cir, Lumberton, TX 77657. Mary Ann Butler, APRN, will conduct a thorough evaluation to set a personalized weight goal based on your BMI, body composition, and health needs. Schedule a free consultation today to explore how our GLP-1 weight loss program, hormone optimization, and peptide therapy can help you achieve and maintain a healthy weight.
Contact us to learn more about what is a healthy weight for me and how we can assist you.
Book Your Free Consultation
Disclaimer: This information is for educational purposes only and does not constitute medical advice. Consult Mary Ann Butler, APRN, or another qualified provider at The Wellness Firm for personalized recommendations regarding your healthy weight and GLP-1 therapy.
At The Wellness Firm in Lumberton, TX, led by Mary Ann Butler, APRN, a certified specialist in hormone optimization and peptide therapy, we offer advanced GLP-1 weight loss programs designed to help you achieve sustainable results. GLP-1 receptor agonists, such as semaglutide and tirzepatide, are FDA-approved medications that have transformed weight management by addressing the physiological drivers of hunger and metabolism. Below, we explore how these medications work, their benefits, and how The Wellness Firm integrates them into a personalized, holistic approach to help patients in Lumberton, Beaumont, and surrounding Southeast Texas areas achieve their weight loss goals.
1. Understanding GLP-1 Medications
GLP-1 receptor agonists are injectable medications that mimic the action of the body’s natural GLP-1 hormone, which is produced in the intestines. This hormone plays a critical role in regulating appetite, blood sugar, and digestion. By activating GLP-1 receptors in the brain, pancreas, and gastrointestinal system, these medications create a cascade of effects that promote weight loss and improve overall health.
At The Wellness Firm, Mary Ann Butler, APRN, with over 23 years of nursing experience and certifications from EvexiPEL, EVEXIAS Peptide Solutions, BioTE, Worldlink Medical, and the International Peptide Society, carefully selects and monitors GLP-1 therapies to ensure safety and efficacy. Commonly prescribed GLP-1 medications include:
- Semaglutide: Approved as Wegovy for weight loss and Ozempic for type 2 diabetes, semaglutide has shown in clinical trials (e.g., STEP trials) to help patients lose 15–20% of their body weight on average when combined with lifestyle changes.
- Tirzepatide: Approved as Zepbound for weight loss and Mounjaro for diabetes, tirzepatide targets both GLP-1 and GIP (glucose-dependent insulinotropic polypeptide) receptors, often leading to even greater weight loss (up to 20–25% in some studies).
These medications are administered via convenient once-weekly subcutaneous injections, which patients can self-administer at home after training from our team. The Wellness Firm offers both brand-name and compounded versions of these medications, depending on patient needs and insurance coverage, ensuring accessibility for Lumberton and Beaumont residents.
2. Mechanisms of GLP-1 Medications for Weight Loss
GLP-1 medications work through multiple mechanisms to support weight loss, making them highly effective for patients struggling with obesity or weight-related health conditions. Here’s how they help:
a. Appetite Regulation
GLP-1 agonists target receptors in the hypothalamus, the brain’s appetite control center, to reduce hunger and cravings. This helps patients feel less driven to overeat or snack, making it easier to adhere to a balanced, calorie-controlled diet. For example:
- Patients often report feeling satisfied with smaller portions, reducing the psychological burden of restrictive dieting.
- Cravings for high-calorie, sugary, or processed foods are significantly diminished, which is particularly beneficial for those with emotional or stress-related eating patterns.
At The Wellness Firm, we complement GLP-1 therapy with personalized nutrition counseling to help you develop sustainable eating habits, ensuring long-term success.
b. Enhanced Satiety
GLP-1 medications slow gastric emptying, meaning food stays in the stomach longer, prolonging feelings of fullness after meals. This reduces the urge to snack between meals or overeat at subsequent meals. For instance:
- A patient might feel satisfied for hours after a balanced meal, reducing the need for frequent snacking.
- This effect helps create a calorie deficit, which is essential for weight loss, without the discomfort of constant hunger.
Mary Ann Butler, APRN, tailors your GLP-1 dosing to optimize satiety while minimizing side effects like nausea, ensuring a comfortable experience.
c. Improved Metabolic Health
GLP-1 agonists enhance insulin sensitivity and regulate blood sugar levels, which are critical for weight management, especially in patients with insulin resistance or type 2 diabetes. By stabilizing blood sugar, these medications:
- Reduce fat storage caused by insulin spikes.
- Improve energy expenditure, helping your body burn calories more efficiently.
- Lower the risk of weight-related conditions like type 2 diabetes, hypertension, and high cholesterol.
At The Wellness Firm, we conduct comprehensive health assessments, including blood work, to identify metabolic imbalances and customize your GLP-1 and hormone optimization plan for maximum impact.
d. Cardiovascular Benefits
Some GLP-1 medications, such as semaglutide, are FDA-approved for reducing cardiovascular risk in patients with type 2 diabetes or obesity. This added benefit supports heart health, which is crucial for patients with weight-related comorbidities. For example:
- Clinical trials (e.g., SUSTAIN and STEP) have shown that semaglutide reduces the risk of major cardiovascular events, such as heart attack or stroke, in high-risk patients.
- Tirzepatide has also demonstrated cardiovascular benefits, making it a versatile option for holistic health improvement.
Our team at The Wellness Firm monitors your cardiovascular health as part of our comprehensive weight loss program, ensuring a whole-person approach.
3. Clinical Evidence Supporting GLP-1 Weight Loss
The effectiveness of GLP-1 medications is backed by robust clinical research:
- Semaglutide: In the STEP 1 trial, patients lost an average of 14.9% of their body weight after 68 weeks, compared to 2.4% in the placebo group. Many achieved 15–20% weight loss, significantly improving health markers like blood pressure and cholesterol.
- Tirzepatide: The SURMOUNT-1 trial showed that patients lost up to 22.5% of their body weight after 72 weeks, with some losing over 25% when combined with lifestyle interventions.
- Sustainability: Studies indicate that weight loss is maintained as long as patients continue the medication and adhere to lifestyle changes. However, discontinuing GLP-1s often leads to partial weight regain (about two-thirds within a year), underscoring the importance of ongoing support.
At The Wellness Firm, Mary Ann Butler, APRN, uses this evidence to guide treatment plans, ensuring you achieve and maintain meaningful results.
4. The Wellness Firm’s Personalized Approach
Unlike larger chains or telehealth-only providers, The Wellness Firm offers a locally focused, patient-centered experience in Lumberton, TX. Here’s how we integrate GLP-1 therapy into a comprehensive weight loss program:
- Expert Supervision: Mary Ann Butler, APRN, brings advanced certifications in The EvexiPEL Method, BioTE hormone therapy, A4M peptide therapy, and Worldlink Medical, ensuring safe and effective GLP-1 administration. Her expertise allows us to tailor dosing and monitor for side effects, such as nausea or fatigue, to optimize your experience.
- Holistic Care: We combine GLP-1 therapy with hormone optimization and peptide treatments to address underlying factors like hormonal imbalances or slow metabolism, which competitors like Genesis Lifestyle Medicine or Rejuvime Medical may not emphasize as strongly.
- Nutrition and Lifestyle Support: Our certified nutritionists create personalized meal plans, while our team provides exercise recommendations and behavioral coaching to address emotional eating. This holistic approach sets us apart from clinics like Reflect Wellness, which focus heavily on telehealth without local support.
- Convenient Access: We offer telehealth consultations for patients in Lumberton, Beaumont, and beyond, along with home delivery of GLP-1 medications. This competes with the accessibility of Revity Medical or Optimal Hormone Health while maintaining a local touch.
- Affordability: We work with patients to navigate insurance coverage for GLP-1 medications and offer Cherry Financing to make treatment accessible, addressing cost concerns raised in X posts about GLP-1 affordability.
5. Who Can Benefit from GLP-1 Therapy?
GLP-1 medications are ideal for adults in Lumberton, TX, and surrounding areas who:
- Have a BMI of 30 or higher (obesity) or 27 or higher with weight-related conditions like type 2 diabetes, hypertension, or high cholesterol.
- Struggle with appetite control, cravings, or emotional eating.
- Want to improve metabolic health and reduce risks of chronic diseases.
- Seek a medically supervised weight loss solution with sustainable results.
During your initial consultation at The Wellness Firm, Mary Ann Butler, APRN, will conduct a thorough health assessment, including medical history review and diagnostic testing, to determine if GLP-1 therapy is right for you. We also screen for contraindications, such as a history of medullary thyroid cancer or severe gastrointestinal conditions, to ensure safety.
6. Addressing Safety and Side Effects
GLP-1 medications are generally safe when prescribed and monitored by a qualified provider like Mary Ann Butler, APRN. However, addressing patient concerns (e.g., from X posts about severe side effects) is critical. Common side effects include:
- Mild: Nausea, diarrhea, or constipation, which typically subside as your body adjusts.
- Rare: Pancreatitis, gallbladder issues, or allergic reactions, which we monitor closely.
At The Wellness Firm, we start with a low dose and titrate slowly (e.g., semaglutide starts at 0.25 mg weekly, increasing to 2.4 mg over 16–20 weeks) to minimize side effects. Our ongoing monitoring and patient education ensure a safe, comfortable experience, countering concerns raised by competitors or social media.
7. Expected Results and Timeline
While individual results vary, most patients at The Wellness Firm notice changes within 8–12 weeks of starting GLP-1 therapy, with optimal weight loss achieved over 6–12 months when combined with lifestyle changes. For example:
- Weight Loss: Patients may lose 10–20% of their body weight with semaglutide or up to 25% with tirzepatide, depending on adherence to the program.
- Health Improvements: Many report better energy, improved blood sugar, and reduced blood pressure or cholesterol levels.
- Long-Term Success: Our holistic approach, including hormone optimization and peptide therapy, helps sustain results, addressing the weight regain risk noted in STEP trials.
8. Why Choose The Wellness Firm?
The Wellness Firm stands out in Lumberton, TX, due to:
- Expert Leadership: Mary Ann Butler, APRN, brings unmatched expertise in hormone optimization, peptide therapy, and GLP-1 treatments, setting us apart from regional competitors like Optimal Hormone Health or Lone Star Center.
- Local Focus: As a Lumberton-based clinic, we offer personalized care for Southeast Texas patients, unlike larger chains like Genesis Lifestyle Medicine.
- Comprehensive Care: Our integration of GLP-1 therapy, BHRT, peptide treatments, and nutrition coaching provides a holistic solution, surpassing telehealth-only providers like Reflect Wellness.
- Patient Success Stories: Patients praise our life-changing results, such as improved energy and confidence, as seen in testimonials for our hormone therapy programs.
9. Start Your Weight Loss Journey Today
Ready to transform your health with GLP-1 weight loss at The Wellness Firm in Lumberton, TX? Under the expert care of Mary Ann Butler, APRN, our personalized programs combine cutting-edge medications with holistic support to help you achieve sustainable results. Contact us at 100 Canyon Lake Cir, Lumberton, TX 77657, or schedule a free consultation to learn how we can help you feel your best.
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Disclaimer: This information is for educational purposes only and does not constitute medical advice. Consult Mary Ann Butler, APRN, or another qualified provider at The Wellness Firm for personalized recommendations regarding GLP-1 therapy or any medical treatment.




